Of course Fernandinho is suspended for the game against Spurs. In his place there are a number of potential replacements with Fabian Delph and Yaya Toure all suitable fits. I do think that Delph will be positioned at left back though, and Toure just hasn’t looked good at all.
Ilkay Gundogan could be Guardiola’s go to in that position, although I wouldn’t bet against him getting forward and Delph covering. In front of German-dinho, if fit, should be David Silva and Kevin De Bruyne.